Sodium/potassium ratio alter is in the blood pressure level alter: chances of population approach for sodium/potassium ratio loss of wellness checkup

Sodium/potassium ratio alter is in the blood pressure level alter: chances of population approach for sodium/potassium ratio loss of wellness checkup

Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± 3.0 to 4.9 ± 2.2, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± 17.4 mmHg) was lower than that in 2017 (132.1 ± 17.9 mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.


Recently, it absolutely was reported that the fresh new salt (Na)/potassium (K) ratio is from the blood pressure level (BP) in the a cross-sectional data [1,2,3,4]. It is asked because higher Na and you will K consumption was identified getting associated with higher and you may reasonable BP, correspondingly [5,6,7]. On top of that, research has been held towards the site philosophy and you can items contributing to the newest Na/K ratio prior to now year [8, 9].

Sodium/potassium proportion changes is actually in the hypertension transform: chances of inhabitants method for salt/potassium ratio reduction in health checkup

From inside the a community means, it is hard for us to evaluate the real Na intake just like the Na consumption are generally examined of the twenty four-h pee collection. Even if multiple equations to have quoting Na consumption cuddli or K consumption having fun with informal put urine was indeed has just created, such equations are not specific adequate to promote views to your some body [10,eleven,12]. Furthermore, once the equation means computing Na, K, and you can creatinine membership during the a laboratory, it takes several weeks to find the outcomes for individuals. Whether or not members realize that salt protection is good for lowering BP, he’s got no chance regarding examining the Na level.

Has just, an excellent Na/K proportion mind-monitoring tool using destination urine is actually dependent . Although it failed to assess the real Na intake peak, it can promote viewpoints regarding your urinary Na/K equilibrium within minutes. Also, a keen interventional or observational data with this specific screen ideal this would-be a useful equipment in order to guess the urinary Na/K ratio [thirteen, 14].

For this reason, although we haven’t any answer to measure the Na/K proportion for the health checkup settings, i believed that assessing brand new urinary Na/K proportion in the a medical checkup website might have the potential to provide opinions with the standard populace about their Na/K ratio that will have an effect on feeling changes, change in step, Na/K ratio cures, and you will BP cures. Inside studies, we assessed perhaps the urinary Na/K proportion changes measured for the Na/K ratio aspect equipment is actually for the BP change separate off confounding points eg bmi (BMI) changes and change into the alcoholic beverages intake and you can compared the brand new BP height and you may urinary Na/K proportion at the people height.

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